Paul Hertzog

Professor Paul Hertzog is Director of the Centre for Innate Immunity and Infectious Diseases; Associate Director of the Hudson Institute of Medical Research; NHMRC Senior Principal Research Fellow; a Research Professor of Monash University; and an Adjunct Professor at the Chinese Academy of Sciences. He obtained his PhD from the University of Melbourne, then undertook postdoctoral training in cancer research at the Eppley Institute of Cancer Research, USA, then the Cancer Research Unit, York, UK. His field of work is innate immunity and specifically the role of type I IFNs in disease. This includes structure-function studies of how different IFNs interact with receptors to elicit different responses; characterisation of the novel IFN epsilon he discovered, in the mucosal immune response to reproductive tract infections including HIV, ovarian and breast cancers, etc. His group also studies the contribution of IFN toxicities to the pathogenesis of multi-organ autoinflammatory diseases. His bioinformatics subgroup uses innovative approaches, develops pipelines and databases to analysing genome-wide responses to IFN. They developed and curate the Interferome® database widely used by international researchers studying IFN signatures in diseases.   His group’s work has been published in eminent journals including Cell, Science,  Nature ImmunologyNature MedicineImmunity, and the Journal of Clinical Investigation, among others. This work resulted in Professor Hertzog being awarded the international 2013 Milstein Award for Excellence in Interferon and Cytokine Research. Professor Hertzog is founder of the Victorian Infection and Immunity Network and its Industry Alliance Program, and he co-convenes the Lorne Infection and Immunity annual conference.

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